Internship: Autonomous Downstream Purification for Monoclonal Antibodies (m/fd)

Description du poste:

Work Your Magic with us!

Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

Start date: August / september
Duration: 6-12 months
Location: Corsier-sur-Vevey
Role Level: Internship

Your role:
* As a member of the Global Drug Substance Development, you will work with a group of motivated scientists who are committed to developing and implementing solutions to support the development of new biological therapeutics processes.
* An innovative autonomous end-to-end monoclonal antibody platform is being developed to integrate perfusion cell culture with continuous downstream processing. Perfusion culture enables sustained high-density cell culture with continuous product harvest, generating a steady stream of cell-free culture fluid suitable for direct integration with automated purification operations.
* You will work on establishing this autonomous system to enable rapid, high-throughput material generation for early-stage development activities, significantly accelerating timelines and reducing manual intervention in the production of monoclonal antibody samples for process development and characterization studies.
* Your mission will focus on automating the critical downstream purification sequence, specifically:
* Affinity capture chromatography on ÄKTA systems using Protein A columns for monoclonal antibody capture.
* Automated low-pH viral inactivation to ensure viral safety.
* Depth filtration for particle removal.
* You will design and execute experiments to characterize individual unit operations, optimize their integration into a continuous workflow, and demonstrate that the autonomous platform consistently produces high-quality monoclonal antibody material suitable for development studies.
* You will be trained to be autonomous, and you will have the opportunity to present your work during various meetings.

Your profile:
* Master/engineer student in biotechnology related fields
* Currently studying
* Highly motivated and autonomous
* Ability to conceptualize, solve complex challenges, and communicate about your project
* Great team spirit
* Previous experience in DSP and/or Automation is a plus
* Python skills is a plus
* Good written and oral knowledge in English, French is a plus

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity