Researcher in Cell Biology / 3D Imaging of Photosymbiosis

Job Description:

Description du poste

Domaine

Sciences du vivant

Contrat

CDI

Intitulé de l'offre

Researcher in Cell Biology / 3D Imaging of Photosymbiosis

Statut du poste

Cadre

Description de l'offre

Photosynthetic organisms (microalgae and plants) are in constant interaction with their environment, responding to various abiotic pressures (temperature, nutrients, light), as well as biotic ones (symbiosis, parasitism). Molecular approaches ('omics') have improved our understanding of the adaptive mechanisms to these changes. However, the cellular architecture and structural organisation of organelles such as the chloroplast and mitochondria must be revealed to fully understand how organisms respond to their environment.

3D electron microscopy has become one of the essential approaches for revealing and deciphering the mechanisms of cellular plasticity. Technological advances and cryogenic sample preparation now make it possible to visualise cellular structures, membrane arrangements, contacts between organelles, and macro-complex structures in their cellular context (in situ structural biology). The laboratory Cell and Plant Physiology (LPCV), which aims to understand the adaptive response of microalgae and plants at multiple scales, has been applying 3D electron microscopy (FIB-SEM) in this field, thanks to the technological environment of IRIG and its collaboration with IBS. This work has led to several publications describing the morphological changes in microalgae in different abiotic and biotic conditions (Uwizeye et al. 2021, PNAS, PMID:34215695; Uwizeye et al. 2020, Nat. Commun, PMID:33594064; Decelle et al. 2022 ISME journal PMID:35804051; Ezzedine et al. Nat Commun).

To further understand subcellular plasticity in microalgae at high resolution (

Profil du candidat

Holder of a PhD in biology or biophysics, you have completed a postdoctoral contract of at least 2 years and have advanced research experience in the field of microscopy and image analysis.
You are an expert in cryo-electron microscopy and image analysis. You have skills in eukaryotic cell biology, electron microscopy, and bioimage analysis. You have a basic knowledge in integrative structural biology, and in AI / deep learning approaches and/or sub-tomogram averaging.
You are comfortable communicating in English, both written and spoken, in a scientific and technical context. You will be required to write scientific articles, design new scientific projects and programmes, and seek funding by responding to local, national, or international calls for proposals. You are able to work as part of a team. You are able to transfer know-how and expertise to junior members of the team and the lab, thanks to your excellent communication skills.
Why Join Us?
By joining IRIG, you will be part of a dynamic and innovative research environment where you have the opportunity to learn, grow, and play a key role within a centre of excellence.
You will also benefit from:
* A state-of-the-art research ecosystem, covering topics with major societal impact
* Training opportunities to strengthen your skills and boost your career
* A works council (CE) rich in social, cultural, and sports benefits
* Practical daily benefits: staff restaurant, 85% transport subsidy, and much more
* An exceptional living environment in Grenoble, in the heart of the mountains, offering a unique balance between urban life and nature
Would you like to be part of the adventure? Apply now and bring your energy to research and innovation.
In line with CEA's commitments to promoting the inclusion of people with disabilities, this position is open to all.
How to Apply
To apply, please send the following documents:
* CV (2-3 pages)
* Research project proposal in English (3-4 pages)
* Contact of 3 to 5 referees
* Application deadline: 21st of August 2026
For any enquiries about the position and application process, please contact: johan.decelle@univ-grenoble-alpes.fr or laurent.blanchoin@cea.fr

Localisation du poste

Site

Grenoble

Localisation du poste

France, Auvergne-Rhône-Alpes, Isère (38)

Ville

Grenoble

Critères candidat

Formation recommandée

PhD in biology or biophysics

Demandeur

Disponibilité du poste

01/10/2026