Research Officer (WW Lab), IMCB

Descripción del puesto:

Position Summary

Job Description and Requirements

A Research Officer is immediately available. The Research Officer will support research activities investigating the molecular mechanisms underlying cancer biology and RNA regulation. The successful candidate will perform a range of molecular and cellular biology experiments, contribute to experimental design and data analysis, maintain laboratory operations, and work collaboratively within a multidisciplinary research team. The role offers opportunities to contribute to high-impact publications and translational research projects.

Key Responsibilities

* Design, execute and optimise molecular and cellular biology experiments to address research objectives.
* Perform routine and advanced laboratory techniques, including nucleic acid and protein analysis, cell culture, gene expression analysis, and molecular cloning.
* Conduct functional studies using genetic and pharmacological approaches to investigate cellular signalling pathways and disease mechanisms.
* Analyse experimental data using appropriate statistical and bioinformatics tools, and maintain accurate experimental records.
* Prepare figures, summaries and reports for internal meetings, grant applications and scientific publications.
* Contribute to manuscript preparation and presentation of research findings at laboratory meetings and scientific conferences.
* Maintain laboratory equipment, manage reagent inventory and ensure compliance with institutional safety and biosafety regulations.
* Assist in supervising undergraduate students, interns and junior laboratory members where appropriate.
* Collaborate effectively with internal and external research partners to support multidisciplinary research projects.
* Perform other research-related duties as assigned.

Required Qualifications

* Bachelor's or Master's degree in Molecular Biology, Cell Biology, Biomedical Sciences, Life Sciences or a related discipline.
* Experience in molecular biology, cell biology or cancer biology research is preferred.
* Strong organisational skills with attention to detail and accurate record keeping.
* Ability to work independently while contributing effectively within a collaborative research environment.
* Excellent written and verbal communication skills.

Preferred Technical Skills

Candidates with experience in one or more of the following techniques are encouraged to apply:

* Mammalian cell culture
* RNA and DNA extraction
* PCR, quantitative RT-PCR and digital PCR
* Molecular cloning and plasmid construction
* CRISPR/Cas9 genome editing
* RNA interference (siRNA/shRNA)
* Western blotting and immunoprecipitation
* Flow cytometry and cell death assays
* Immunofluorescence and confocal microscopy
* ELISA and protein quantification assays
* RNA sequencing and transcriptomic data analysis
* Epitranscriptomics (e.g. m⁶A RNA methylation)
* Cancer cell signalling and functional assays
* Basic bioinformatics and statistical analysis (e.g. R, GraphPad Prism)

Desired Attributes

* Demonstrated interest in molecular mechanisms of disease and translational biomedical research.
* Strong analytical and problem-solving abilities.
* Willingness to learn new experimental techniques and computational approaches.
* Ability to manage multiple projects and meet deadlines.
* High level of scientific integrity and commitment to reproducible research