Research Officer (HWP Lab) IMCB

Descrizione del lavoro:

Position Overview

We are seeking a highly motivated and detail-oriented Research Officer to support ongoing research projects targeting metabolic pathways in the development of therapeutic strategies towards obesity and

its related complications. The successful candidate will play a critical role in driving bench-side execution, focusing on in vivo rodent studies, mammalian cell culture, and standard molecular biology workflows.

This role offers excellent opportunities to work within a multidisciplinary team and manage end-to-end experimental data packages.

Key Responsibilities

* Mouse Colony Management: Manage mouse colony maintenance (breeding, weaning, ear notching/tagging, and genotyping) and track animal cohorts.
* Experimental Handling: Perform routine in vivo procedures including dosing (subcutaneous, intraperitoneal, oral gavage) and regular monitoring of body weight, food intake, and overall animal welfare.
* In-Life & Endpoint Sampling: Assist in executing specific metabolic or functional assessments (e.g., glucose/insulin tolerance tests, body composition, metabolic chambers) and perform terminal tissue collection (blood collection, perfusion, and harvesting/dissection of target organs).
* In Vitro & Wet Lab Work: Maintain primary or immortalized mammalian cell cultures and execute standard wet-lab and molecular biology assays (RNA/protein extraction, RT-qPCR, Western blotting, and ELISAs).
* Data & Lab Management: Maintain meticulous and reproducible laboratory notebooks and protocols. Support general lab operations, buffer preparation and reagent stock-taking and collaborate and assist other researchers and collaborators on related projects. Communicate regularly with supervisor, Principal Investigator and rest of the lab to discuss scientific progress and direction.

Qualifications & Requirements

Education & Experience

* Degree: Bachelor's or Master's degree in Biological Sciences, Life Sciences, Pharmacology, Biochemistry, or a highly related discipline.
* Research Experience: Minimum of 6 to 12 months of hands-on laboratory and mouse work experience in a biomedical laboratory (prior academic internships, Final Year Projects, or industry attachment counts).

Technical Skills

* Essential: Hands-on experience with basic rodent handling and restraint. Competence in basic molecular biology and cellular assays (cell culture, PCR/qPCR, Western blot).
* Highly Preferred: Direct technical proficiency in basic dosing routes (IP, SC, PO), terminal tissue/blood collection and mouse colony management.
* Bonus / Advantageous: Prior completion of certified animal care and use courses (e.g., RCULA certification).
* Experience running specialized metabolic profiling (e.g., GTT/ITT, metabolic chambers) or performing specific surgical models.
Soft Skills

* Strong organizational discipline with a rigorous approach to experimental controls, reproducibility, and data integrity.
* Excellent collaborative mindset; capable of multitasking across multiple project streams and coordinating shared resources with other lab members.
* Strong written and verbal communication skills in English to effectively summarize data for regular lab updates