Vodilni raziskovalec I / Principal Scientist I

Description du poste:

Salary Range:EUR46,550.00 - EUR86,450.00

Job Description Summary#LI-Hybrid

Location: Menges, Slovenia

Role Purpose:
Our R&D unit in Mengeš is looking for a motivated and experienced scientist in field of Downstream Processing (DSP) to join us and help us develop a diverse portfolio of biotherapeutic modalities.

As a Principal Scientist you must demonstrate a broad and in-depth knowledge of technologies in recombinant protein production and purification to evaluate the developability of various biologics modalities covered by Novartis Biomedical Research and Development units, ranging from traditional antibodies to advanced biologics formats and mixed modalities, ensuring quality of material delivered and eventually enabling lead candidate selection.

You will lead a team of associates where you will be responsible for a continuously strong culture of team spirit and integrity, as well as providing development opportunities for associates on different levels.

We offer a stimulating work environment, ample opportunities for growth and development, and the chance to make a significant impact on the future of medicine. If you are a motivated and talented scientist with a passion for biomedical research, we invite you to apply and become a part of our dynamic team at Novartis.

Naša R&D enota v Mengšu išče motiviranega in izkušenega raziskovalca s področja izolacije bioloških učinkovin (DSP), ki se nam bo pridružil in nam pomagal razvijati raznolik portfelj bioterapevtikov.

Kot Vodilni raziskovalec morate izkazovati široko in poglobljeno poznavanje tehnologij proizvodnje in čiščenja rekombinantnih proteinov, da boste lahko ocenili razvojni potencial različnih bioloških terapevtskih kandidatov, ki jih pokrivajo enote Novartis Biomedicinske raziskave in Razvoj, od tradicionalnih protiteles do naprednih bioloških formatov in mešanih modalnosti, pri čemer zagotavljate kakovost dostavljenega materiala in na koncu omogočate izbor vodilnega kandidata.

Vodili boste ekipo sodelavcev, pri čemer boste odgovorni za stalno močno kulturo timskega duha in integritete ter za zagotavljanje razvojnih priložnosti za sodelavce na različnih ravneh.

Ponujamo spodbudno delovno okolje, številne priložnosti za rast in razvoj ter možnost pomembnega vpliva na prihodnost medicine. Če ste motiviran in nadarjen znanstvenik s strastjo do biomedicinskih raziskav, vas vabimo, da se prijavite in postanete del naše dinamične ekipe v Novartisu.

Job Description

Key responsibilities:

* Coordinate and execute downstream processing of recombinantly expressed proteins (e.g. monoclonal antibodies, multispecific antibodies and other therapeutic proteins) from suspension CHO culture from small to large scale (up to 200L)

* Act as senior production expert and Production lead in project teams ensuring optimal project support and high quality for all deliverables

* Drive the therapeutic protein production strategy in R&D Mengeš, working globally in a matrix organization to support a diverse biologics pipeline transitioning into clinical development

* Drive and lead technology projects for protein purification and conjugation in close collaboration with related line functions; incorporate latest technologies and knowledge into research activities and ongoing projects 

* Foster streamlined processes and optimally use of capacities as well as continued innovation, incorporating latest technologies and knowledge

* Effectively manage resources, project activities, timelines, maintain a strong customer focus and set respective objectives

* Provide leadership and clear guidance to the team, optimally leveraging the expertise and experience of individuals

* Drive a culture of collaboration, integrity, and team development, and ensure a safe, empowering, and inspiring working environment

Minimum Requirements - What you will bring to the role:

* PhD in biochemistry, chemistry, biotechnology or a related field with at least 2 years experience in pharmaceutical industry; or MSc degree with at least 5 years experience in pharmaceutical industry

* Strong theroretical and practical background in Downstream Processing of monoclonal and multispecific antibodies, including liquid chromatography on Aekta systems, filtration and centrifugation technologies

* Proven experience in successfully prioritizing and keeping complex project timelines, excellent organizational skills with the ability to run multiple projects in parallel

* Strong experience in experimental design, data analysis workflows and report generation

* Distinguished team spirit and scientific drive

* High flexibility combined with excellent organizational and communication skills

* Fluency in English (oral/written)

Desirable Requirements:

* Experience in CHO cell culture / Upstream Processing

Benefits & Rewards

At Novartis, we're committed to reimagining medicine together - and rewarding the people who make it happen.

Expected Annual Base Salary Range for role: EUR46,550 to EUR86,450

The base salary offered is determined based on gender-neutral objectives, such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and upon joining Novartis will be reviewed periodically.

In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters.

The rewards of being part of our team go far beyond base pay and incentives. We also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs. In addition, we provide flexible and hybrid working options, where possible, and minimum 14 weeks paid parental leave.

Skills Desired